At present, and although many factors have been shown to be strongly associated with discontinuation or non adherence,55 our ability to distinguish or characterise non adherent patients is poor. Additionally, adherence has been assessed in diverse ways, many of which are not standardised or replicable (eg, some studies confuse physician non adherence to prescription guidelines with patient non adherence to prescribed treatments, or use very different criteria for defining non adherent patients, or mix nave drug cohorts with experienced drug cohorts). Furthermore, not all studies use the same definitions regarding clinical outcomes (eg, some studies consider that the patient has discontinued treatment when switching from one anticoagulant to another)..
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This in from NHL insider John Shannon, talking to Reid Wilkins of CHED about the NHL selection of Toronto and Edmonton as playoff hub cities: looks like Edmonton and Toronto are the two hub cities. Twitter Shannon said: indications pointing to a in Canada for the Hubs. Amongst other things, the increased virus cases in 36 states, have Edmonton and Toronto has the hub cities for the NHL.
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